Afsaneh Sadeghzadeh Bazargan has completed her dermatology specialty at the age of 30 years from shahid beheshti University of Medical Sciences, Tehran, Iran. She won the top 5% in the Iran dermatology board exam and now she is the assistant professor of Iran University of medical sciences, Iran.
Lichen planus is an idiopathic and chronic in?ammatory disease that affects the skin and the mucous membranes, and has been associated with an increased risk for cardiovascular diseases. Hyperhomocysteinemia has been regarded as a risk factor for atherosclerosis and cardiovascular diseases. Increased plasma fibrinogen levels are also associated with increased risk of myocardial infarction. The main aim of this study is the evaluation of common carotid artery mean intima media wall thickness, serum fibrinogen and homocysteine levels in patients with lichen planus. Forty?three patients with lichen planus and 43 age, gender and body mass index (BMI) matched healthy controls (from general population without the disease) were included in this study. Compared to the healthy controls, patients had statistically significant greater mean intima media wall thickness of the common carotid artery. Moreover, a positive correlation was observed between lichen planus and increased serum homocysteine and c?reactive protein levels. Early diagnosis of atherosclerosis in patients with lichen planus might afford better prophylaxis, including weight control and/or lipid profile monitoring. Measurement of the mean intima media wall thickness of the common carotid artery by duplex high?resolution B?mode ultrasound scanning could be beneficial as a valuable method for early diagnosis of atherosclerosis in lichen planus.
Dr. Afshin Javili, an Iranian doctor, is a Cosmetic Surgeon and ENT Specialist. He is a medical doctor from Tehran University of Medical Science (1997), ENT Specialist from O.O.Bogomolets National Medical University (NMU) Kiev Ukraine (2009). Since 2012 he has been working on Non Surgical Aesthetic Procedures, he has gone through these procedures for hundreds of his patients in Iran. In 2014 he started working on Lifting and Filling Threads and now Dr. Javili is one of the most experienced and best doctors in the field and non-surgical methods of aesthetic medicine overly in the world. He has already managed and held a dozen teaching courses and workshops as a teacher so he is one of the most experienced and well-known teachers in the field in the world. He speaks Persian, English, Russian, German, Ukrainian and Turkish. He was born in 1970 in Iran and recently moved to Turkey and lives in Istanbul.
What are these?: They are absorbable medical threads that will be inserted under the skin for Aesthetic problems or remodeling. What’s the importance of them?: They are an excellent alternative therapy of big and complicated surgeries in Aesthetic medicine and the procedure is Non-Surgical and very easier. In which kind of branches of medicine they might be used?: Dermatology, E.N.T, Plastic Surgery, Neurology, Neurosurgery, Maxillofacial Surgery, Ophthalmology. What are their indications?: Wrinkles , dynamic and static lines of skin, Treatment of asymmetries, Lifting of skin, Skin tightening and contour laxity, Rejuvenation and delay cutaneous aging, Volume loss under the skin, Alternative of botox and fillers, Scars, Sharpening of columns , lines and borders of skin, Skin brightness. What are they made of?: There are 3 types of threads now. P.D.O (polydioxanone) P.L.L.A (Poly-L-Lactic Acid) P.C.L (Polycaprolactone) How does it works?: At first it has an instant skin lifting and filling effects through mechanical effects, after that resolving process will begin and among this, cellular renewal , collagen stimulation and neovascularisation will be occurred and it will be caused to improve skin texture, fine lines ,stretching, elasticity and skin tightening. How long does it take for threads to dissolve? P.D.O 3-6 MONTHS P.L.L.A 12-18 MONTHS P.C.L 24-36 MONTHS How soon will we see results and how long they remains?: The best result will be seen after 3 months of insertion and depends on the type of the thread. It will be continued more than 2 years or up to many years. What are their benefits?: minimally invasive procedure, short time (15 – 30 minutes), surprisingly safe treatment (very few side effects), very natural, tissue making, cost effective in compare of surgery, ambulatory procedure, long lasting effects. After the procedure: Some mild swelling and soreness for 1 to 2 days and a mild sensation of tightness up to 2 weeks and with a good ice packing there is no bruising. Side effects: If happened are easily manageable and serious side effects are mostly related to the technique of insertion so if the doctor is skilled , well trained and experienced there are no side effects at all.
Judith D has completed her dermatology formation in the General Hospital “Dr. Manuel Gea González”. She is the chief of the dermatology deparment at Instituto de Ciencias Médicas y Nutrición “Salvador Zubirán” in Mexico since 2011. She has more than 150 publications that have been cited over 650 times, with an H- index of 16. She’s member of the Mexican Academy of Dermatology, National Academy of Medicine, Mexican Academy of Surgery, and honorable member of the American Dermatological Association. She is also a level II member of the Sistema Nacional de Investigadores (National System of Researchers).
Tattoos have been part of human culture since ancient civilizations; nevertheless, they have experienced an increase in popularity in the last decades. In the United States approximately 36% of the population under 30 has a tattoo, bringing with it, a considerable amount of medical complications of different nature and severity, especially infections of multiples etiologies. In recent years, the practice of tattoing has taken a relevant role at the medical area too. Some examples are the marking of radiation zones in patients with neoplasms; tattoos to hide scars or hypopigmented areas in vitiligo or burned patients; tattoos are used in corneal abnormal coloration too. Dermatologists are forced to deepen their knowledge about tattoos: their aplication method, most frequent complications, treatments of the complications as well as the available techniques for removing them.
Dr Nisha Prakash has completed her undergraduate course, MBBS from the prestigious institution Bangalore Medical College and Research Institute in India. She has completed her MD in Dermatology, Venereology and Leprology from Rajarajeswari Medical College and Hospital which is affiliated to Rajiv Gandhi University of Health Sciences University, Karnataka, India. She is currently practising at Cutis Academy Of Health Sciences, Bengaluru.
Background: Acanthosis nigricans (AN) is a dermatosis that manifests as asymptomatic and symmetrical darkening in intertriginous areas and is associated with endocrine disturbances or malignancy. The features of metabolic syndrome (MetS) include hyperglycemia, hypertriglyceridemia, low high?density lipoprotein cholesterol, central obesity and hypertension. Aims and Objectives: (1) To study the fasting and post-prandial blood sugar level, lipid profile, blood pressure and waist circumference in patients with AN and compare the values in healthy controls. (2) To determine the association between the presence of benign acquired AN and MetS (biochemical parameters and anthropometric variables). Materials and Methods: A descriptive case–control study with 100 cases of AN and 100 healthy controls without AN was conducted between December 2016 and November 2017 to assess the association between AN and metabolic variables. Results: In this study, out of the 100 cases evaluated, 57% had MetS diagnosed by the National Cholesterol Education Program and Adult Treatment Panel III, of which 35 were females and 22 males. Among 100 cases of AN, 31 had hypertension (P = 0.438), 57 had elevated triglycerides (P = 0.007), 33 had elevated fasting blood sugar (P = 0.061), 76 had decreased HDL cholesterol (P = 0.000045), and 78 had increased WC (P = 0.00463). The association of AN with MetS was highly significant in the study population (P = 0.000017; as P < 0.05?significant; P < 0.01?highly significant). Conclusion: In this study, 57 patients with AN had deranged metabolic variables suggesting the presence of MetS. This study shows that AN could be a marker for MetS. Hence, clinicians should assess patients with AN for metabolic and biochemical parameters to advise regarding lifestyle modification and prevent future cardiovascular complications.
Sham AlZahabi has graduated from the American University in Cairo with MSc in Chemistry, was senior RnD researcher at local cosmetic factory, Eva cosmetics for 3 years. Following her masters, got awarded several scholarships in both Cambridge University and Oxford University to continue her research. She went to Cambridge to begin her PhD journey, where she studied biomimicry of skin modeling in the group of Professor Duer, and interrupted her study to come back to Egypt and open her skin clinic, Dao Derma, where now she’s continuing both.
This work aims to investigate the potential advantage of using Prickly Pear (PP) seed oil to develop nanostructured lipid carrier (NLC) for topical delivery of vitamin A. The release patterns of four PP-based NLC formulations with varying amounts of surfactant to solid lipid ratio, and amounts of Prickly Pear Seed oil have been developed using the hot homogenization method, and compared with a solid lipid nanoparticle (SLN) formulation that is free of PP oil. The effect of the variation in the constituting matrix of the nano-carriers on entrapment efficiency, in-vitro release behavior, and ex-vivo permeation using Franz Diffusion Cell, was investigated. Additionally, particle size and polydispersity index (PDI) upon storage, zeta potential, and thermal behavior were characterized. PP-based NLCs exhibited smaller particle size in the range of 215-244 nm, and PDI < 0.3. In contrast, SLN having no PP oil had a larger diameter of 365nm, with heterogeneous distribution (0.92 PDI). In assessing the in-vitro release, an inverse relationship was observed between the diffusion flux and the entrapment efficiency. The changes in the constituting matrix of the NLCs lead to a significant potential variation in their properties, and hence allowing it to be tailored for specific usages.
Chief Dermato-laser & Hair Transplant Surgeon In Aura Skin Institute, Chandigarh, India. Program Director For IADVL Fellowship in ‘Lasers & Aesthetic Dermatology’. Recipient of Young Dermatologist Forum Award,2008 for work on Cutaneous Vasculitis in Dermacon 2008. Reviewer for prestigious journals like IJDVL ,Stem cell investigation journal,, JCAS, JCD, JCMS and IDOJ. Filed a Patent protocol on non-surgical facelift. Innovated LA-PEEST , a novel fast acting Vitiligo surgery. Proposed a Global drooping and wrinkle classification for aging face. Invited faculty in ‘International Conference on Regenerative Surgery, Rome, 2017and also for WCOCD, Croatia,2018 to present innovative research work on FUE & PRP Therapy.
Background: Treating melasma is a challenge due to suboptimal efficacy and recurrence encountered with most modalities. There is inadequate literature regarding the use of lasers for melasma in Indian skin. We compared three modalities SSR (Super Skin Rejuvenation 540 nm), PQSNDY (pixel Q-switched Nd: YAG 1064 nm), and ablative pixel-Er: YAG (2940 nm) laser in melasma, amongst Indian patients. Sixty patients of recalcitrant melasma were enrolled and randomized into three groups with 20 patients each. These were treated with SSR, low fluence PQSNDY, and pixel-Er: YAG, respectively, for five sessions at 3-week intervals. Results were evaluated using modified melasma area severity index (mMASI) by blinded comparison of digital photographs at baseline, each visit and 6 months (i.e. 2 months after the last session).All groups showed a highly significant reduction in the mMASI score (p < .001). Pixel-Er: YAG maximally reduced mMASI and homogeneity (p < .001), while the other groups showed a more uniform fading. Epidermal melasma had best results with SSR and PQSNDY (p < .001), while recalcitrant cases of dermal and mixed melasma with pixel-Er: YAG laser (p < .001). There was no persistent or rebound pigmentation observed. All three modalities are effective and safe for melasma in Indian patients. Fractional technology, low fluences, adequate recovery time between sessions and a sound maintenance plan ensure efficacy and safety.